منابع مشابه
Norfloxacin disposition after sequentially increasing oral doses.
Single doses of norfloxacin (200, 400, 800, 1,200, and 1,600 mg) or placebo were administered orally at weekly intervals to 14 healthy male volunteers in a double-blind study. Norfloxacin was measured in serum and urine by high-pressure liquid chromatography with UV detection. The concentrations of this drug in serum peaked 1 to 2 h after each dose; the mean peak values for increasing doses wer...
متن کاملSimultaneous Spectrophotometric Estimation of Norfloxacin and Ornidazole in Tablet Dosage Form
Three simple, accurate and economical methods have been developed for the estimation of norfloxacin and ornidazole in tablet dosage form. First method is based on the simultaneous equations, wavelengths selected for analysis were 273.0 nm (lambda(max) of norfloxacin) and 318.5 nm (lambda(max) of ornidazole), respectively, in 0.1N NaOH. Second method is Q-analysis method, based on absorbance rat...
متن کاملPK-PD modelling of norfloxacin after oral administration in rabbits
Norfloxacin posses a wide spectrum of activity, excellent tissue penetration and is rapidly bactericidal at low concentrations and hence an attempt was made to integrate reported pharmacodynamic data with pharmacokinetic data of norfloxacin after oral administration in rabbits to determine its effectiveness against common bacterial pathogens infecting rabbits. Pharmacokinetic data were obtained...
متن کاملTablet as human: How intensity and stability of the user-tablet relationship influences users' impression formation of tablet computers
When can computers seem ‘‘human’’? How do users form identity impressions of computers? In an examination of the ways in which users form impressions of their tablet computers, this study offers a new perspective by allowing users to verbalize their impressions of their products. Findings from in-depth interviews revealed two basic constructs that inform users’ impression formation – intensity ...
متن کاملNorfloxacin sesquihydrate
IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: 1-ethyl-6-fluoro-4-oxo-7-(piperazin-4-ium-1-yl)-1,4-dihydro-quinoline-3-carboxyl-ate sesquihydrate], C(16)H(18)FN(3)O(3)·1.42H(2)O, N-H⋯O and O-H⋯O hydrogen bonds assemble the mol-ecules in a two-dimensional layered corrugated sheet structure parallel to the b axis. The water mol-ecules are disordered [occupancies 0.741 (11) and 0...
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ژورنال
عنوان ژورنال: Japanese Journal of Hospital Pharmacy
سال: 1989
ISSN: 2185-9477,0389-9098
DOI: 10.5649/jjphcs1975.15.181